Ontology highlight
ABSTRACT:
SUBMITTER: Spitali P
PROVIDER: S-EPMC5867073 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Spitali Pietro P Hettne Kristina K Tsonaka Roula R Sabir Ekrem E Seyer Alexandre A Hemerik Jesse B A JBA Goeman Jelle J JJ Picillo Esther E Ergoli Manuela M Politano Luisa L Aartsma-Rus Annemieke A
Journal of cellular and molecular medicine 20180214 4
Muscular dystrophies are characterized by a progressive loss of muscle tissue and/or muscle function. While metabolic alterations have been described in patients'-derived muscle biopsies, non-invasive readouts able to describe these alterations are needed in order to objectively monitor muscle condition and response to treatment targeting metabolic abnormalities. We used a metabolomic approach to study metabolites concentration in serum of patients affected by multiple forms of muscular dystroph ...[more]