Ontology highlight
ABSTRACT:
SUBMITTER: Burgos A
PROVIDER: S-EPMC5869015 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
eLife 20180312
Rapid and efficient escape behaviors in response to noxious sensory stimuli are essential for protection and survival. Yet, how noxious stimuli are transformed to coordinated escape behaviors remains poorly understood. In <i>Drosophila</i> larvae, noxious stimuli trigger sequential body bending and corkscrew-like rolling behavior. We identified a population of interneurons in the nerve cord of <i>Drosophila</i>, termed Down-and-Back (DnB) neurons, that are activated by noxious heat, promote noci ...[more]