Ontology highlight
ABSTRACT:
SUBMITTER: Levine JM
PROVIDER: S-EPMC5869021 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Levine Jennifer M JM Whitton John A JA Ginsberg Jill P JP Green Daniel M DM Leisenring Wendy M WM Stovall Marilyn M Robison Leslie L LL Armstrong Gregory T GT Sklar Charles A CA
Cancer 20180116 5
<h4>Background</h4>Survivors of childhood cancer are at risk of nonsurgical premature menopause (NSPM). To the authors' knowledge, risk factors for NSPM and its impact on reproduction remain poorly defined.<h4>Methods</h4>The menopausal status of 2930 survivors diagnosed between 1970 and 1986 (median age, 6 years [range, birth-20 years]) who were aged > 18 years at the time of the current study (median age, 35 years [range, 18-58 years]) was compared with 1399 siblings. NSPM was defined as the c ...[more]