Ontology highlight
ABSTRACT:
SUBMITTER: Fenoglio C
PROVIDER: S-EPMC5870004 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Fenoglio Chiara C Scarpini Elio E Serpente Maria M Galimberti Daniela D
Journal of Alzheimer's disease : JAD 20180101 3
Alzheimer's disease (AD) and frontotemporal dementia (FTD) represent the first cause of dementia in senile and pre-senile population, respectively. A percentage of cases have a genetic cause, inherited with an autosomal dominant pattern of transmission. The majority of cases, however, derive from complex interactions between a number of genetic and environmental factors. Gene variants may act as risk or protective factors. Their combination with a variety of environmental exposures may result in ...[more]