Ontology highlight
ABSTRACT:
SUBMITTER: Yi M
PROVIDER: S-EPMC5870075 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Yi Ming M Yu Shengnan S Qin Shuang S Liu Qian Q Xu Hanxiao H Zhao Weiheng W Chu Qian Q Wu Kongming K
Journal of hematology & oncology 20180327 1
Immune checkpoint inhibitors (ICIs) therapy is a novel strategy for cancer treatments in recent years. However, it was observed that most patients treated with ICIs could not get benefit from the therapy, which led to the limitation of clinical application. Motivated by potent and durable efficacy of ICIs, oncologists endeavor to explore the mechanisms of resistance to ICIs and increase the drug sensitivity. It is known that heterogeneity of gut microbiome in populations may result in different ...[more]