Dataset Information
BreakPoint Surveyor: a pipeline for structural variant visualization.
Ontology highlight
ABSTRACT: Summary
BreakPoint Surveyor (BPS) is a computational pipeline for the discovery, characterization, and visualization of complex genomic rearrangements, such as viral genome integration, in paired-end sequence data. BPS facilitates interpretation of structural variants by merging structural variant breakpoint predictions, gene exon structure, read depth, and RNA-sequencing expression into a single comprehensive figure.Availability and implementation
Source code and sample data freely available for download at https://github.com/ding-lab/BreakPointSurveyor, distributed under the GNU GPLv3 license, implemented in R, Python and BASH scripts, and supported on Unix/Linux/OS X operating systems.Contact
lding@wustl.edu.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Wyczalkowski MA
PROVIDER: S-EPMC5870665 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
BreakPoint Surveyor: a pipeline for structural variant visualization.
Bioinformatics (Oxford, England) 20171001 19
<h4>Summary</h4>BreakPoint Surveyor (BPS) is a computational pipeline for the discovery, characterization, and visualization of complex genomic rearrangements, such as viral genome integration, in paired-end sequence data. BPS facilitates interpretation of structural variants by merging structural variant breakpoint predictions, gene exon structure, read depth, and RNA-sequencing expression into a single comprehensive figure.<h4>Availability and implementation</h4>Source code and sample data fre ...[more]