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ResistoMap-online visualization of human gut microbiota antibiotic resistome.


ABSTRACT:

Abstract

We created ResistoMap—a Web-based interactive visualization of the presence of genetic determinants conferring resistance to antibiotics, biocides and heavy metals in human gut microbiota. ResistoMap displays the data on more than 1500 published gut metagenomes of world populations including both healthy subjects and patients. Multiparameter display filters allow visual assessment of the associations between the meta-data and proportions of resistome. The geographic map navigation layer allows to state hypotheses regarding the global trends of antibiotic resistance and correlates the gut resistome variations with the national clinical guidelines on antibiotics application.

Availability and implementation

ResistoMap was implemented using AngularJS, CoffeeScript, D3.js and TopoJSON. The tool is publicly available at http://resistomap.rcpcm.org.

Contact

yarygin@phystech.edu.

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Yarygin KS 

PROVIDER: S-EPMC5870722 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Publications

ResistoMap-online visualization of human gut microbiota antibiotic resistome.

Yarygin Konstantin S KS   Kovarsky Boris A BA   Bibikova Tatyana S TS   Melnikov Damir S DS   Tyakht Alexander V AV   Alexeev Dmitry G DG  

Bioinformatics (Oxford, England) 20170701 14


<h4>Abstract</h4>We created ResistoMap—a Web-based interactive visualization of the presence of genetic determinants conferring resistance to antibiotics, biocides and heavy metals in human gut microbiota. ResistoMap displays the data on more than 1500 published gut metagenomes of world populations including both healthy subjects and patients. Multiparameter display filters allow visual assessment of the associations between the meta-data and proportions of resistome. The geographic map navigati  ...[more]

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