Ontology highlight
ABSTRACT:
SUBMITTER: Hayes BME
PROVIDER: S-EPMC5872323 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Hayes Brigitte M E BME Bleackley Mark R MR Anderson Marilyn A MA van der Weerden Nicole L NL
Journal of fungi (Basel, Switzerland) 20180206 1
Antimicrobial peptides are widespread in nature and are produced by many organisms as a first line of defence against pathogens. These peptides have a broad range of biological activities, such as antibacterial or antifungal activities and act with varied mechanisms of action. A large number of the peptides are amphipathic α-helices which act by disrupting plasma membranes and allowing leakage of intracellular contents. However, some peptides have more complex mechanisms of action that require i ...[more]