GIGGLE: a search engine for large-scale integrated genome analysis.
Ontology highlight
ABSTRACT:
SUBMITTER: Layer RM
PROVIDER: S-EPMC5872823 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Publications
GIGGLE: a search engine for large-scale integrated genome analysis.
Layer Ryan M RM Pedersen Brent S BS DiSera Tonya T Marth Gabor T GT Gertz Jason J Quinlan Aaron R AR
Nature methods 20180108 2
GIGGLE is a genomics search engine that identifies and ranks the significance of genomic loci shared between query features and thousands of genome interval files. GIGGLE (https://github.com/ryanlayer/giggle) scales to billions of intervals and is over three orders of magnitude faster than existing methods. Its speed extends the accessibility and utility of resources such as ENCODE, Roadmap Epigenomics, and GTEx by facilitating data integration and hypothesis generation. ...[more]
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