Ontology highlight
ABSTRACT:
SUBMITTER: Wu P
PROVIDER: S-EPMC5873366 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Wu Pensee P Farrell William E WE Haworth Kim E KE Emes Richard D RD Kitchen Mark O MO Glossop John R JR Hanna Fahmy W FW Hanna Fahmy W FW Fryer Anthony A AA
Epigenetics 20180125 2
Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450K array analysis to determine changes to the epigenome in a unique cohort of maternal blood DNA from 11 pregnant women prior to GDM development relative to matched controls. Hierarchical clustering segregated the samples into 2 distinct clusters comprising GDM and healthy ...[more]