Ontology highlight
ABSTRACT:
SUBMITTER: Cho NJ
PROVIDER: S-EPMC5874023 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Cho Nam-Jun NJ Han Dong-Jae DJ Lee Ji-Hye JH Jang Si-Hyong SH Kang Jeong Suk JS Gil Hyo-Wook HW Park Samel S Lee Eun Young EY
PloS one 20180328 3
Klotho deficiency is relevant to renal fibrosis and podocyte injury in vivo and in vitro. We examined whether histological findings of renal biopsy specimens were associated with the levels of soluble klotho in humans. We investigated renal biopsy specimens of 67 patients and detailed microscopic findings were reviewed. Soluble serum/urinary klotho and urinary angiotensinogen were assessed by enzyme-linked immunosorbent assays, and tissue klotho expression was assessed by immunohistochemical sta ...[more]