Ontology highlight
ABSTRACT:
SUBMITTER: Tsang S
PROVIDER: S-EPMC5874062 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Tsang Siny S Duncan Glen E GE Dinescu Diana D Turkheimer Eric E
PloS one 20180328 3
<h4>Background</h4>Body Mass Index (BMI), like most human phenotypes, is substantially heritable. However, BMI is not normally distributed; the skew appears to be structural, and increases as a function of age. Moreover, twin correlations for BMI commonly violate the assumptions of the most common variety of the classical twin model, with the MZ twin correlation greater than twice the DZ correlation. This study aimed to decompose twin correlations for BMI using more general skew-t distributions. ...[more]