Galectins as Molecular Targets for Therapeutic Intervention.
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ABSTRACT:
SUBMITTER: Dings RPM
PROVIDER: S-EPMC5877766 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Publications
Galectins as Molecular Targets for Therapeutic Intervention.
Dings Ruud P M RPM Miller Michelle C MC Griffin Robert J RJ Mayo Kevin H KH
International journal of molecular sciences 20180319 3
Galectins are a family of small, highly conserved, molecular effectors that mediate various biological processes, including chemotaxis and angiogenesis, and that function by interacting with various cell surface glycoconjugates, usually targeting β-galactoside epitopes. Because of their significant involvement in various biological functions and pathologies, galectins have become a focus of therapeutic discovery for clinical intervention against cancer, among other pathological disorders. In thi ...[more]
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