Ontology highlight
ABSTRACT:
SUBMITTER: Kamande JW
PROVIDER: S-EPMC5877822 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
Kamande Joyce W JW Lindell Maria A M MAM Witek Małgorzata A MA Voorhees Peter M PM Soper Steven A SA
Integrative biology : quantitative biosciences from nano to macro 20180201 2
Blood samples from patients with plasma cell disorders were analysed for the presence of circulating plasma cells (CPCs) using a microfluidic device modified with monoclonal anti-CD138 antibodies. CPCs were immuno-phenotyped using a CD38/CD56/CD45 panel and identified in 78% of patients with monoclonal gammopathy of undetermined significance (MGUS), all patients with smouldering and symptomatic multiple myeloma (MM), and none in the controls. The burden of CPCs was higher in patients with sympto ...[more]