Laboratory biomarkers for venous thromboembolism risk in patients with hematologic malignancies: A review.

ABSTRACT: INTRODUCTION:Despite high rates of venous thromboembolism (VTE) among patients with hematologic malignancies, few tools exist to assist providers in identifying those patients at highest risk for this potentially fatal complication. Laboratory biomarkers, such as d-dimer, have demonstrated utility in some clinical settings to distinguish patients at increased risk. MATERIALS AND METHODS:We performed a systematic review of the literature utilizing search terms including "biomarker", "venous thromboembolism", "hematologic malignancy", "lymphoma", "myeloma" and "leukemia" in the Medline database. A total of 25 studies investigating laboratory biomarkers of increased thrombotic risk in the setting of hematologic malignancy were identified and included in this review. RESULTS AND CONCLUSIONS:Th

SUBMITTER: Samuelson Bannow BT 

PROVIDER: S-EPMC5879008 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature