Ontology highlight
ABSTRACT:
SUBMITTER: Chahal M
PROVIDER: S-EPMC5880267 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Chahal Manik M Pleasance Erin E Grewal Jasleen J Zhao Eric E Ng Tony T Chapman Erin E Jones Martin R MR Shen Yaoqing Y Mungall Karen L KL Bonakdar Melika M Taylor Gregory A GA Ma Yussanne Y Mungall Andrew J AJ Moore Richard A RA Lim Howard H Renouf Daniel D Yip Stephen S Jones Steven J M SJM Marra Marco A MA Laskin Janessa J
Cold Spring Harbor molecular case studies 20180402 2
Metastatic adenoid cystic carcinomas (ACCs) can cause significant morbidity and mortality. Because of their slow growth and relative rarity, there is limited evidence for systemic therapy regimens. Recently, molecular profiling studies have begun to reveal the genetic landscape of these poorly understood cancers, and new treatment possibilities are beginning to emerge. The objective is to use whole-genome and transcriptome sequencing and analysis to better understand the genetic alterations unde ...[more]