Ontology highlight
ABSTRACT:
SUBMITTER: Vangapandu HV
PROVIDER: S-EPMC5882591 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Leukemia & lymphoma 20171003 6
Chronic lymphocytic leukemia (CLL) is an indolent B-cell malignancy in which cells reside in bone marrow, lymph nodes, and peripheral blood, each of which provides a unique microenvironment. Although the levels of certain proteins are reported to induce, changes in the CLL cell proteome in the presence of bone marrow stromal cells have not been elucidated. Reverse-phase protein array analysis of CLL cells before and 24 h after stromal cell interaction revealed changed levels of proteins that reg ...[more]