Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC5883027 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Wang Junjie J Yang Weilin W Wang Tao T Chen Xiaoyong X Wang Jiancheng J Zhang Xiaoran X Cai Chuang C Zhong Beilong B Wu Jiabin J Chen Zhenguang Z Xiang Andy Peng AP Huang Weijun W
Scientific reports 20180403 1
Mesenchymal stromal cells (MSCs) have been considered as one of the pivotal type of cells composing the tumor microenvironment. Although contact-dependent mechanisms and paracrine factors are thought to collaborate in governing the MSCs-based effects on tumors progression, the underlying mechanisms remain largely unknown. In particular, the involvement of MSCs-derived cytokines in the epithelial-mesenchymal transition (EMT) of esophageal squamous cell carcinoma (ESCC) has not been clarified. In ...[more]