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Evolution of Sex Determination Loci in Atlantic Salmon.


ABSTRACT: Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations in Atlantic salmon (Salmo salar). To characterize each, whole genome sequencing was performed to 30-fold depth of coverage using 20 fish representing each of three identified sex lineages. SNP polymorphism reveals male fish carry a single copy of the male specific region, consistent with an XX/XY or male heterogametric sex system. Haplotype analysis revealed deep divergence between the putatively ancestral locus on chromosome 2, compared with loci on chromosomes 3 and 6. Haplotypes in fish carrying either the chromosome 3 or 6 loci were nearly indistinguishable, indicating a founding event that occurred following the speciation event that defined Salmo salar from other salmonids. These findings highlight the evolutionarily fluid state of sex determination systems in salmonids, and resolve to the sequence level differences in animals with divergent sex lineages.

SUBMITTER: Kijas J 

PROVIDER: S-EPMC5884791 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Evolution of Sex Determination Loci in Atlantic Salmon.

Kijas James J   McWilliam Sean S   Naval Sanchez Marina M   Kube Peter P   King Harry H   Evans Bradley B   Nome Torfinn T   Lien Sigbjørn S   Verbyla Klara K  

Scientific reports 20180404 1


Teleost fish exhibit a remarkable diversity in the control of sex determination, offering the opportunity to identify novel differentiation mechanisms and their ecological consequences. Here, we perform GWAS using 4715 fish and 46,501 SNP to map sex determination to three separate genomic locations in Atlantic salmon (Salmo salar). To characterize each, whole genome sequencing was performed to 30-fold depth of coverage using 20 fish representing each of three identified sex lineages. SNP polymor  ...[more]

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2024-04-22 | MSV000094589 | MassIVE