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The efficacy and safety of high-intensity focused ultrasound ablation of benign thyroid nodules.

ABSTRACT: High-intensity focused ultrasound (HIFU) is a promising form of thermal ablation of benign thyroid nodules, but evidence supporting its use is scarce. The present review evaluated the efficacy and safety of single-session HIFU treatment of benign thyroid nodules. As reported in the literature, the extent of nodule shrinkage following treatment ranged from 48.8% to 68.8%. Like other forms of ablation, the shrinkage rate was greatest in the first 3-6 months, and the best responders were patients with small (?10 mL) nodules. Complications were uncommon, but temporary vocal cord palsy occurred in 3%-4% of patients, and was related to the distance between the HIFU beam and the recurrent laryngeal nerve. Despite being safe and efficacious, a larger-scale prospective trial is required.

SUBMITTER: Lang BH

PROVIDER: S-EPMC5885474 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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The efficacy and safety of high-intensity focused ultrasound ablation of benign thyroid nodules.

Lang Brian H BH Wu Arnold L H ALH

Ultrasonography (Seoul, Korea) 20171010 2

High-intensity focused ultrasound (HIFU) is a promising form of thermal ablation of benign thyroid nodules, but evidence supporting its use is scarce. The present review evaluated the efficacy and safety of single-session HIFU treatment of benign thyroid nodules. As reported in the literature, the extent of nodule shrinkage following treatment ranged from 48.8% to 68.8%. Like other forms of ablation, the shrinkage rate was greatest in the first 3-6 months, and the best responders were patients w ...[more]

PMID: 29207852

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