Ontology highlight
ABSTRACT:
SUBMITTER: Schwartz R
PROVIDER: S-EPMC5886015 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Schwartz Russell R Schäffer Alejandro A AA
Nature reviews. Genetics 20170213 4
Rapid advances in high-throughput sequencing and a growing realization of the importance of evolutionary theory to cancer genomics have led to a proliferation of phylogenetic studies of tumour progression. These studies have yielded not only new insights but also a plethora of experimental approaches, sometimes reaching conflicting or poorly supported conclusions. Here, we consider this body of work in light of the key computational principles underpinning phylogenetic inference, with the goal o ...[more]