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Effect of exercise on pain and functional capacity in breast cancer patients.

ABSTRACT: To assess the influence of combined training on pain, fatigue, maximal oxygen uptake (VO2 max), body mass index (BMI), flexibility, and strength in patients with breast cancer.A controlled pilot study with 28 patients undergoing chemotherapy, radiation therapy, and clinical observation in a renowned cancer treatment center; the patients were aged from 30 to 59 years old and were not engaged in physical training for three months previously. The Study Group (SG) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20 s and was performed in sets of three repetitions. The Control Group (CG) received only the standard hospital treatment. Participants were evaluated at the beginning of the study to establish a baseline and reevaluated at the end of 12 weeks.Patients in the SG showed a significant decrease in total pain points (p?=?0.0047), pain intensity (p?=?0.0082), and the extent to which pain interfered with their daily life (p?=?0.0047). There was an increase in maximum oxygen uptake (p?=?0.0001), flexibility (p?=?0.0001), and strength on both sides (right p?=?0.0001 and left p?=?0.0008). No significant differences were observed in fatigue (p?=?0.0953) or BMI (p?=?0.6088).Combined training was effective in decreasing pain and increasing VO2 max, flexibility and static strength in patients with breast cancer.NCT03061773 . Registered on February 19, 2017, 'retrospectively registered'.

SUBMITTER: Reis AD

PROVIDER: S-EPMC5889570 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Effect of exercise on pain and functional capacity in breast cancer patients.

Reis Andréa Dias AD Reis Andréa Dias AD Pereira Paula Tamara Vieira Teixeira PTVT Diniz Renata Rodrigues RR de Castro Filha Jurema Gonçalves Lopes JGL Dos Santos Alcione Miranda AM Ramallo Bianca Trovello BT Filho Florentino Assenço Alves FAA Navarro Francisco F Garcia João Batista Santos JBS

Health and quality of life outcomes 20180406 1

<h4>Purpose</h4>To assess the influence of combined training on pain, fatigue, maximal oxygen uptake (VO<sub>2</sub> max), body mass index (BMI), flexibility, and strength in patients with breast cancer.<h4>Methods</h4>A controlled pilot study with 28 patients undergoing chemotherapy, radiation therapy, and clinical observation in a renowned cancer treatment center; the patients were aged from 30 to 59 years old and were not engaged in physical training for three months previously. The Study Gro ...[more]

PMID: 29625622

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Project description:ImportancePreserving functional capacity is a key element in the care continuum for patients with esophagogastric cancer. Prehabilitation, a preoperative conditioning intervention aiming to optimize physical status, has not been tested in upper gastrointestinal surgery to date.ObjectiveTo investigate whether prehabilitation is effective in improving functional status in patients undergoing esophagogastric cancer resection.Design, setting, and participantsA randomized clinical trial (available-case analysis based on completed assessments) was conducted at McGill University Health Centre (Montreal, Quebec, Canada) comparing prehabilitation with a control group. Intervention consisted of preoperative exercise and nutrition optimization. Participants were adults awaiting elective esophagogastric resection for cancer. The study dates were February 13, 2013, to February 10, 2017.Main outcomes and measuresThe primary outcome was change in functional capacity, measured with absolute change in 6-minute walk distance (6MWD). Preoperative (end of the prehabilitation period) and postoperative (from 4 to 8 weeks after surgery) data were compared between groups.ResultsSixty-eight patients were randomized, and 51 were included in the primary analysis. The control group were a mean (SD) age, 68.0 (11.6) years and 20 (80%) men. Patients in the prehabilitation group were a mean (SD) age, 67.3 (7.4) years and 18 (69%) men. Compared with the control group, the prehabilitation group had improved functional capacity both before surgery (mean [SD] 6MWD change, 36.9 [51.4] vs -22.8 [52.5] m; P < .001) and after surgery (mean [SD] 6MWD change, 15.4 [65.6] vs -81.8 [87.0] m; P < .001).Conclusions and relevancePrehabilitation improves perioperative functional capacity in esophagogastric surgery. Keeping patients from physical and nutritional status decline could have a significant effect on the cancer care continuum.Trial registrationClinicalTrials.gov Identifier: NCT01666158.

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Effect of exercise on pain and functional capacity in breast cancer patients.

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Effect of exercise on pain and functional capacity in breast cancer patients.

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