Ontology highlight
ABSTRACT:
SUBMITTER: Kityo C
PROVIDER: S-EPMC5890670 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
The Journal of antimicrobial chemotherapy 20170901 9
<h4>Background</h4>Pretreatment HIV drug resistance (PDR) can impair virological response to ART, jeopardizing effective treatment for children.<h4>Methods</h4>Children aged ≤12 years initiated first-line ART in Uganda during 2010-11. Baseline and 6 monthly viral load (VL) and genotypic resistance testing if VL >1000 copies/mL was done. The 2015 IAS-USA mutation list and Stanford algorithm were used to score drug resistance mutations (DRMs) and susceptibility. Virological failure (VF) was define ...[more]