Ontology highlight
ABSTRACT:
SUBMITTER: Kyriakopoulos CE
PROVIDER: S-EPMC5891129 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Kyriakopoulos Christos E CE Chen Yu-Hui YH Carducci Michael A MA Liu Glenn G Jarrard David F DF Hahn Noah M NM Shevrin Daniel H DH Dreicer Robert R Hussain Maha M Eisenberger Mario M Kohli Manish M Plimack Elizabeth R ER Vogelzang Nicholas J NJ Picus Joel J Cooney Matthew M MM Garcia Jorge A JA DiPaola Robert S RS Sweeney Christopher J CJ
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20180131 11
Purpose Docetaxel added to androgen-deprivation therapy (ADT) significantly increases the longevity of some patients with metastatic hormone-sensitive prostate cancer. Herein, we present the outcomes of the CHAARTED (Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer) trial with more mature follow-up and focus on tumor volume. Patients and Methods In this phase III study, 790 patients with metastatic hormone-sensitive prostate cancer were equ ...[more]