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Light-Induced Remodeling of Physically Crosslinked Hydrogels Using Near-IR Wavelengths.

ABSTRACT: Poly([6-bromo-7-hydroxycoumarin-4-yl]methyl methacrylate)-based triblock copolymers were synthesized by first preparing PMAA-PEG-PMAA triblocks using ATRP. 6-Bromo-4-chloromethyl-7-hydroxycoumarin was conjugated to PMAA-PEG-PMAA using 1,8-diazabicycloundec-7-ene (DBU). Rheological measurements were conducted using a HR-2 rheometer with a UV illumination accessory (TA Instruments). Single-photon uncaging was performed as previously described.20 Two-photon uncaging was performed using a LSM (Zeiss) equipped with a Ti: Sapphire laser (Coherent). All values reported as mean ± std. dev. unless otherwise stated. See Supporting Information for experimental details.

SUBMITTER: Zhu C

PROVIDER: S-EPMC5892418 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature

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Light-Induced Remodeling of Physically Crosslinked Hydrogels Using Near-IR Wavelengths.

Zhu Congcong C Bettinger Christopher J CJ

Journal of materials chemistry. B 20140128 12

Poly([6-bromo-7-hydroxycoumarin-4-yl]methyl methacrylate)-based triblock copolymers were synthesized by first preparing PMAA-PEG-PMAA triblocks using ATRP. 6-Bromo-4-chloromethyl-7-hydroxycoumarin was conjugated to PMAA-PEG-PMAA using 1,8-diazabicycloundec-7-ene (DBU). Rheological measurements were conducted using a HR-2 rheometer with a UV illumination accessory (TA Instruments). Single-photon uncaging was performed as previously described.<sup>20</sup> Two-photon uncaging was performed using a ...[more]

PMID: 29651335

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