Ontology highlight
ABSTRACT:
SUBMITTER: Chanthavanich P
PROVIDER: S-EPMC5893197 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Chanthavanich Pornthep P Limkittikul Kriengsak K Sirivichayakul Chukiat C Chokejindachai Watcharee W Hattasingh Weerawan W Pengsaa Krisana K Surangsrirat Surachai S Srisuwannaporn Termsang T Kaewma Benjawan B Yoksan Sutee S Jun Gao G Zhumu Bai B
Human vaccines & immunotherapeutics 20180116 4
Inactivated mouse-brain-derived Japanese encephalitis vaccine has a worrisome safety profile and the live attenuated vaccine is unsuitable in immunodeficiency. This study aimed to evaluate the immunogenicity and safety of an inactivated chromatographically purified Vero-cell-derived JE vaccine (CVI-JE, Beijing P-3 strain) in children. 152 healthy Thai children, with an average (SD) age of 14.4 (3.8) months, received 3 doses of CVI-JE on days 0, 7-28, and one year. Homologous JE neutralizing anti ...[more]