Identification of aberrant circulating miRNAs in Parkinson's disease plasma samples.
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ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC5893342 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Publications
Identification of aberrant circulating miRNAs in Parkinson's disease plasma samples.
Chen Lei L Yang Junxiu J Lü Jinhui J Cao Shanshan S Zhao Qian Q Yu Zuoren Z
Brain and behavior 20180219 4
<h4>Objective</h4>To detect the aberrant expression of circulating miRNAs and explore the potential early diagnostic biomarkers in patients with Parkinson's disease (PD).<h4>Methods</h4>Plasma samples were collected from 25 treatment-naïve PD-diagnosed patients and 25 healthy controls followed by a real-time PCR-based miRNA screening analysis of neuron disease-related miRNAs.<h4>Results</h4>A subset of miRNAs with aberrant expression levels in the plasma of PD-diagnosed patients were identified ...[more]
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