Ontology highlight
ABSTRACT:
SUBMITTER: Jensen T
PROVIDER: S-EPMC5893377 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Jensen Thomas T Abdelmalek Manal F MF Sullivan Shelby S Nadeau Kristen J KJ Green Melanie M Roncal Carlos C Nakagawa Takahiko T Kuwabara Masanari M Sato Yuka Y Kang Duk-Hee DH Tolan Dean R DR Sanchez-Lozada Laura G LG Rosen Hugo R HR Lanaspa Miguel A MA Diehl Anna Mae AM Johnson Richard J RJ
Journal of hepatology 20180202 5
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome; its rising prevalence parallels the rise in obesity and diabetes. Historically thought to result from overnutrition and a sedentary lifestyle, recent evidence suggests that diets high in sugar (from sucrose and/or high-fructose corn syrup [HFCS]) not only increase the risk of NAFLD, but also non-alcoholic steatohepatitis (NASH). Herein, we review the experimental and clinical evidence that fructose prec ...[more]