Ontology highlight
ABSTRACT:
SUBMITTER: Sidiqi MH
PROVIDER: S-EPMC5894263 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Sidiqi M Hasib MH Aljama Mohammed A MA Muchtar Eli E Buadi Francis K FK Warsame Rahma R Lacy Martha Q MQ Dispenzieri Angela A Dingli David D Leung Nelson N Gonsalves Wilson I WI Kumar Shaji K SK Kapoor Prashant P Kourelis Taxiarchis V TV Hogan William J WJ Gertz Morie A MA
Blood advances 20180401 7
We evaluated the impact of light chain type, lambda (λ) or kappa (κ), on disease features and outcomes in patients with immunoglobulin light chain (AL) amyloidosis receiving stem cell transplant at the Mayo Clinic between October 2002 and August 2016. Patients with λ AL amyloidosis had higher rates of renal and neurological involvement (λ 69% vs κ 57%, <i>P</i> = .02 and λ 16% vs κ 9%, <i>P</i> = .03, respectively). Patients with κ AL amyloidosis had more hepatic involvement (λ 7% vs κ 18%, <i>P ...[more]