EZH2 Expression in Naturally Occurring Canine Tumors.
Ontology highlight
ABSTRACT:
SUBMITTER: Choi HJ
PROVIDER: S-EPMC5897971 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Publications
EZH2 Expression in Naturally Occurring Canine Tumors.
Choi Hyun-Ji HJ Lee Han-Byul HB Park Hyun-Kyu HK Cho Sung-Min SM Han Hyo-Jeong HJ Lee Sang-Joon SJ Lee Ji-Young JY Nam Su-Jeong SJ Cho Eun-Ho EH Son Woo-Chan WC
Comparative medicine 20180401 2
Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in various normal and tumorous dog tissues and compared these patterns with those of the corresponding human tissues. Immunohistochemical analysis showed positive staining for EZH2 in 76 of 82 cases of canine tumors, whereas ...[more]
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