Utilizing Animal Models of Infantile Spasms.
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ABSTRACT:
SUBMITTER: Dulla CG
PROVIDER: S-EPMC5898247 | biostudies-literature | 2018 Mar-Apr
REPOSITORIES: biostudies-literature
Publications
Infantile spasms are a devastating epileptic encephalopathy characterized by early life spasms and later seizures. Clinical outcomes of infantile spasms are poor and therapeutic options are limited with significant adverse effects. Therefore, new strategies to treat infantile spasms are of the utmost importance. Animals models of infantile spasms are a critical component of developing new therapies. Here, we review current chronic animal models of infantile spasms and consider future advances th ...[more]
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