Engineering nanoreactors using bacterial microcompartment architectures.
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ABSTRACT:
SUBMITTER: Plegaria JS
PROVIDER: S-EPMC5899066 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Publications
Engineering nanoreactors using bacterial microcompartment architectures.
Plegaria Jefferson S JS Kerfeld Cheryl A CA
Current opinion in biotechnology 20171013
Bacterial microcompartments (BMCs) are organelles that encapsulate enzymes involved in CO<sub>2</sub> fixation or carbon catabolism in a selectively permeable protein shell. Here, we highlight recent advances in the bioengineering of these protein-based nanoreactors in heterologous systems, including transfer and expression of BMC gene clusters, the production of template empty shells, and the encapsulation of non-native enzymes. ...[more]
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