Ontology highlight
ABSTRACT:
SUBMITTER: Liu S
PROVIDER: S-EPMC5899142 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Liu Shiyu S Wei Yuan Y Zhou Xuedong X Zhang Keke K Peng Xian X Ren Biao B Chen Vivian V Cheng Lei L Li Mingyun M
Scientific reports 20180413 1
The enzyme alanine racemase (Alr) has been a new target for the development of antibacterial drugs based on the involvement of D-Ala in bacterial cell wall biosynthesis. Our previous study noted that Alr is essential for the growth and interspecies competitiveness of S. mutans, the major causative organism of dental caries. However, physiological activity and cariogenicity of S. mutans affected by Alr remains unknown. The current study examined the biofilm biomass, biofilm structure, extracellul ...[more]