Ontology highlight
ABSTRACT:
SUBMITTER: Lin CY
PROVIDER: S-EPMC5902714 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Lin Cheng-Yuan CY Zhao Ling L Huang Tao T Lu Lin L Khan Mahjabin M Liu Jie J Zhong Linda L D LLD Cai Zong-Wei ZW Fan Bao-Min BM Wong Anderson O L AOL Bian Zhao-Xiang ZX
Frontiers in physiology 20180410
Spexin is a novel hormone involved in obesity and diabetes while its biofunctional significance in lipid metabolism is still to be comprehended. Global metabolomic analysis in the present study revealed multiple metabolic pathways altered by spexin intraperitoneal (<i>i.p</i>.) injection in rat serum, which are highlighted by the changes in several bile acid metabolites. In rats, spexin (300 μg/kg) could dramatically reduce hepatic and circulating total bile acids (TBA) level compared with the c ...[more]