Developmental Trajectories of Executive and Verbal Processes in Children with Phenylketonuria.
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ABSTRACT:
SUBMITTER: Hawks ZW
PROVIDER: S-EPMC5902806 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Developmental Trajectories of Executive and Verbal Processes in Children with Phenylketonuria.
Hawks Zoë W ZW Strube Michael J MJ Johnson Neco X NX Grange Dorothy K DK White Desirée A DA
Developmental neuropsychology 20180212 3
Phenylketonuria (PKU) is a hereditary disorder characterized by disrupted phenylalanine metabolism and cognitive impairment. However, the precise nature and developmental trajectory of this cognitive impairment remains unclear. The present study used a verbal fluency task to dissociate executive and verbal processes in children with PKU (n = 23; 7-18 years) and controls (n = 44; 7-19 years). Data were collected at three longitudinal timepoints over a three-year period, and the contributions of a ...[more]
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