Ontology highlight
ABSTRACT:
SUBMITTER: Lissemore JI
PROVIDER: S-EPMC5904107 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Lissemore Jennifer I JI Sookman Debbie D Gravel Paul P Berney Alexandre A Barsoum Amir A Diksic Mirko M Nordahl Thomas E TE Pinard Gilbert G Sibon Igor I Cottraux Jean J Leyton Marco M Benkelfat Chawki C
Translational psychiatry 20180418 1
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these treatment modalities. Here, we used positron emission tomography and the α-[<sup>11</sup>C]methyl-L-tryptophan tracer to examine the changes in brain regional serotonin synthesis capacity in OCD patients following treatment with CBT or SSRI treatment. Si ...[more]