Ontology highlight
ABSTRACT:
SUBMITTER: Zhang S
PROVIDER: S-EPMC5905468 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Zhang Sheng S Jiang Jiakai J Chen Zhan Z Wang Yafeng Y Tang Weifeng W Liu Chao C Liu Longgen L Chen Yu Y
OncoTargets and therapy 20180411
<h4>Background</h4>Leptin (<i>LEP</i>) and LEP receptor (<i>LEPR</i>) polymorphisms may be associated with the development of cancer.<h4>Methods</h4>In this study, we selected five functional <i>LEP</i> and <i>LEPR</i> single-nucleotide polymorphisms (SNPs) and conducted a case-control study to determine the relationship of <i>LEP</i> and <i>LEPR</i> polymorphisms with hepatocellular carcinoma (HCC) risk in Eastern Chinese Han population. There were 584 HCC cases and 923 cancer-free controls inc ...[more]