Ontology highlight
ABSTRACT:
SUBMITTER: Moberly AH
PROVIDER: S-EPMC5906445 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Moberly Andrew H AH Schreck Mary M Bhattarai Janardhan P JP Zweifel Larry S LS Luo Wenqin W Ma Minghong M
Nature communications 20180418 1
Respiration and airflow through the nasal cavity are known to be correlated with rhythmic neural activity in the central nervous system. Here we show in rodents that during conditioned fear-induced freezing behavior, mice breathe at a steady rate (~4 Hz), which is correlated with a predominant 4-Hz oscillation in the prelimbic prefrontal cortex (plPFC), a structure critical for expression of conditioned fear behaviors. We demonstrate anatomical and functional connections between the olfactory pa ...[more]