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Novel naphthylpyridines from cobalt-catalyzed cyclotrimerization of a chiral diyne.

ABSTRACT:

Abstract

The concise synthesis of a novel chiral diyne substrate for the assembly of chiral naphthylpyridines was described and different conditions for the cobalt-catalyzed co-cyclotrimerization with nitriles investigated. The products are novel naphthylpyridines possessing configurationally stable biaryl axes.

Graphical abstract

SUBMITTER: Trommer V

PROVIDER: S-EPMC5906485 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Novel naphthylpyridines from cobalt-catalyzed cyclotrimerization of a chiral diyne.

Trommer Volkmar V Fischer Fabian F Hapke Marko M

Monatshefte fur chemie 20171128 4

<h4>Abstract</h4>The concise synthesis of a novel chiral diyne substrate for the assembly of chiral naphthylpyridines was described and different conditions for the cobalt-catalyzed co-cyclotrimerization with nitriles investigated. The products are novel naphthylpyridines possessing configurationally stable biaryl axes.<h4>Graphical abstract</h4> ...[more]

PMID: 29681656

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