Ontology highlight
ABSTRACT:
SUBMITTER: Heikhmakhtiar AK
PROVIDER: S-EPMC5906510 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Heikhmakhtiar Aulia Khamas AK Ryu Ah Jin AJ Shim Eun Bo EB Song Kwang-Soup KS Trayanova Natalia A NA Lim Ki Moo KM
Medical & biological engineering & computing 20171103 5
This study hypothesized that a left ventricular assist device (LVAD) shortens the electromechanical delay (EMD) by mechanical unloading. The goal of this study is to examine, by computational modeling, the influence of LVAD on EMD for four heart failure (HF) cases ranging from mild HF to severe HF. We constructed an integrated model of an LVAD-implanted cardiovascular system, then we altered the Ca<sup>2+</sup> transient magnitude, with scaling factors 1, 0.9, 0.8, and 0.7 representing HF1, HF2, ...[more]