Is daily physical activity affected by dynamic hyperinflation in adults with cystic fibrosis?

ABSTRACT: BACKGROUND:The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF). METHODS:Thirty-four clinically stable CF were studied. All patients undertook incremental cardiopulmonary exercise testing (CPET). CPET-related measurements included: oxygen uptake (V'O2), carbon dioxide production (V'CO2), ventilatory profile, work rate (W), inspiratory capacity (IC), end-expiratory lung volume (EELV). PA was assessed using the accelerometer SenseWear Pro3 Armband. RESULTS:Exercise tolerance was reduced in most of patients and the mean V'O2,peak value was 75.2% of predicted (28.5?±?4.8 ml/min/kg). Seventy % of patients responded to CPET with dynamic hyperinflation. Higher incidence of dynamic hyperinflation was found in CF males compared to CF females (p?=?0.026). Patients who developed dynamic hyperinflation during CPET had higher vigorous PA (p?=?0.01) and more total energy expenditure (p?=?0.006) than patients who did not. EELV? was related to activities requiring vigorous intensity and total energy expenditure (R?=?0.46, p?=?0.001; R?=?0.57, p?

SUBMITTER: Savi D 

PROVIDER: S-EPMC5907710 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature