Ontology highlight
ABSTRACT:
SUBMITTER: Chen XL
PROVIDER: S-EPMC5908128 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Journal of cellular and molecular medicine 20180307 5
DHX15 plays a role in leukaemogenesis and leukaemia relapse. However, the mechanism underlying the transcriptional regulation of DHX15 in ALL has not been elucidated. Our present study aimed to explore the functional promoter region of DHX15 and to investigate the transcription factors controlling the transcription of this gene. A luciferase assay performed with several truncated constructs identified a 501-bp region as the core promoter region of DHX15. Site-directed mutagenesis, electrophoreti ...[more]