Ontology highlight
ABSTRACT:
SUBMITTER: Listernick R
PROVIDER: S-EPMC5908242 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Annals of neurology 20070301 3
Optic pathway glioma (OPG), seen in 15% to 20% of individuals with neurofibromatosis type 1 (NF1), account for significant morbidity in young children with NF1. Overwhelmingly a tumor of children younger than 7 years, OPG may present in individuals with NF1 at any age. Although many OPG may remain indolent and never cause signs or symptoms, others lead to vision loss, proptosis, or precocious puberty. Because the natural history and treatment of NF1-associated OPG is different from that of spora ...[more]