Dietary patterns, BCMO1 polymorphisms, and primary lung cancer risk in a Han Chinese population: a case-control study in Southeast China.

ABSTRACT: BACKGROUND:We investigated whether BCMO1 variants and dietary patterns are associated with lung cancer risk. METHODS:Case-control study including 1166 lung cancer cases and 1179 frequency matched controls was conducted for three BCMO1 variants (rs6564851, rs12934922, and rs7501331) and four dietary patterns were investigated. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs). RESULTS:The rs6564851, rs12934922, and rs7501331 were not found to be associated with lung cancer risk (P?>?0.05). In multivariable-adjusted models, compared to the lowest quartile of the score on the "fruits and vegetables" pattern, the highest quintile was associated with a 78.4% decreased risk (OR Q4 vs. Q1?=?0.216; 95% CI, 0.164-0.284; P for trend

SUBMITTER: He F 

PROVIDER: S-EPMC5909209 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature