Dataset Information
Five-year clinical follow-up of the STENTYS self-apposing stent in complex coronary anatomy: a single-centre experience with report of specific angiographic indications.
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ABSTRACT: Objectives
We sought to investigate angiographic indications for the use of the STENTYS technique and evaluated the long-term safety and clinical efficacy of the stent.Background
Coronary lesions involving complex anatomy, including aneurysmatic, ectatic, or tapered vessel segments often carry a substantial risk of stent malapposition. The self-apposing stent technique may reduce the risk of stent malapposition and therefore improve clinical outcomes.Methods
A total of 120 consecutive patients treated with the STENTYS stent were included (drug-eluting stent (DES) n?=?101, bare-metal stent (BMS) n?=?19). All lesions were scored for angiographic indications for the STENTYS stent, including aneurysms, ectasias, tapering, absolute diameters, bifurcation lesions, and saphenous vein grafts. Off-line quantitative coronary angiography analyses were performed pre-procedure and post-procedure. Five years follow-up was obtained including cardiac death, target vessel myocardial infarction (TV-MI), target vessel revascularisation, stent thrombosis, and the composite endpoint target vessel failure (cardiac death, TV-MI and target vessel revascularisation).Results
Angiographic indications for STENTYS use were aneurysm (30%), ectasia (19%), tapering (27%), bifurcation lesions (8%), and saphenous vein graft lesions (16%) and absolute diameters (22%). Mean maximal diameter was 4.51?±?0.99?mm. At 5?year follow-up target vessel failure rates were 24.1% in the total cohort (DES 22.8% vs. BMS 33%, p?=?0.26). Definite stent thrombosis rate was 3.8% at 5?year follow-up in this cohort with complex and high-risk lesions (DES 4.5% vs. BMS 0%, p?=?0.39).Conclusions
Angiographic indications for the use of the self-apposing stent were complex lesions with atypical coronary anatomy. Our data showed reasonable stent thrombosis rates at 5?year follow-up, considering the high-risk lesion characteristics.
SUBMITTER: Lu H
PROVIDER: S-EPMC5910317 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Publications
Five-year clinical follow-up of the STENTYS self-apposing stent in complex coronary anatomy: a single-centre experience with report of specific angiographic indications.
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20180501 5
<h4>Objectives</h4>We sought to investigate angiographic indications for the use of the STENTYS technique and evaluated the long-term safety and clinical efficacy of the stent.<h4>Background</h4>Coronary lesions involving complex anatomy, including aneurysmatic, ectatic, or tapered vessel segments often carry a substantial risk of stent malapposition. The self-apposing stent technique may reduce the risk of stent malapposition and therefore improve clinical outcomes.<h4>Methods</h4>A total of 12 ...[more]