Ontology highlight
ABSTRACT:
SUBMITTER: Yamakawa S
PROVIDER: S-EPMC5910596 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Yamakawa Shumpei S Morino Yoshiaki Y Honda Masanao M Wada Hiroshi H
EvoDevo 20180421
<h4>Background</h4>Although retinoic acid (RA) signaling plays a crucial role in the body patterning of chordates, its function in non-chordate invertebrates, other than its mediation of environmental cues triggering metamorphosis in cnidarians, is largely unknown. We investigated the role of RA signaling in the metamorphosis of starfish (Echinodermata).<h4>Results</h4>We found that exogenous RA treatment induced metamorphosis in starfish larvae. In contrast, inhibitors of RA synthesis and RA re ...[more]