Integrative analysis of competing endogenous RNA network focusing on long noncoding RNA associated with progression of cutaneous melanoma.
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ABSTRACT:
SUBMITTER: Xu S
PROVIDER: S-EPMC5911588 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
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Integrative analysis of competing endogenous RNA network focusing on long noncoding RNA associated with progression of cutaneous melanoma.
Xu Siyi S Sui Jing J Yang Sheng S Liu Yufeng Y Wang Yan Y Liang Geyu G
Cancer medicine 20180309 4
Cutaneous melanoma (CM) is the most malignant tumor of skin cancers because of its rapid development and high mortality rate. Long noncoding RNAs (lncRNAs), which play essential roles in the tumorigenesis and metastasis of CM and interplay with microRNAs (miRNAs) and mRNAs, are hopefully considered to be efficient biomarkers to detect deterioration during the progression of CM to improve the prognosis. Bioinformatics analysis was fully applied to predict the vital lncRNAs and the associated miRN ...[more]
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