Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC5911615 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Zhang Qianye Q Zheng Xiao X Li Xiaoxia X Sun Deyu D Xue Ping P Zhang Guopei G Xiao Mingyang M Cai Yuan Y Jin Cuihong C Yang Jinghua J Wu Shengwen S Lu Xiaobo X
Cancer medicine 20180308 4
Colorectal cancer (CRC), as a malignant tumor of lower digestive tract, has been found to have an increasing morbidity and mortality in China. It was particularly important to find some earlier biomarkers to predict the risk and prognosis. In this study, several polymorphisms on 3'UTR of three DNA repair genes including MLH3 rs10862, ERCC1 rs3212986, ERCC1 rs735482, ERCC1 rs2336219, and OGG1 rs1052133 were chosen by bioinformatics exploration, and then, a case-control study of 200 CRC cases and ...[more]