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Efficient Multicomponent Active Template Synthesis of Catenanes.

ABSTRACT: We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.

SUBMITTER: Lewis JEM

PROVIDER: S-EPMC5916464 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Efficient Multicomponent Active Template Synthesis of Catenanes.

Lewis James E M JEM Modicom Florian F Goldup Stephen M SM

Journal of the American Chemical Society 20180402 14

We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation. ...[more]

PMID: 29558129

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