Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation.
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ABSTRACT:
SUBMITTER: Papanicolaou GA
PROVIDER: S-EPMC5916792 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Publications
Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation.
Papanicolaou Genovefa A GA Lee Yeon Joo YJ Young James W JW Seshan Surya V SV Boruchov Adam M AM Chittick Gregory G Momméja-Marin Herve H Glezerman Ilya G IG
American journal of kidney diseases : the official journal of the National Kidney Foundation 20150117 5
Polyomavirus-associated nephropathy (PVAN) is common in patients who have undergone kidney transplantation and has been reported in hematopoietic stem cell (HSC) transplant recipients. Aside from reduction of immunosuppression, few therapeutic options exist for treatment of PVAN. We report a case of PVAN in a severely immunocompromised allogeneic HSC transplant recipient that was treated with brincidofovir without reduction of immunosuppression. We review our institutional experience of PVAN in ...[more]
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